Abstract: The experiment was aimed to increase profitability in the poultry production by determining the optimum level of minerals-vitamins premix supplementation for broiler chicks under the prevailing tropical conditions. The commercially produced minerals-vitamins premix used was NUTRIMIX Broiler Starter Premix. Sixty white unsexed chicks of Anak hybrid were used in 4 experimental diets with incremental levels of minerals-vitamins premix viz; 0.00%, 0.125%, 0.25%, and 0.375%. Completely randomized design (CRD) was used for the experiment. The treatment diets were fed to the broilers from week 2 – week 5. Average daily live weight gain; average feed intake and; final weight gain at week 9 were determined. Feed conversion ratio was calculated. Analysis of variable (ANOVA) test was used to analyze the parameters and Fisher’s least significant difference (F-lsd) at 0.05 probability level was used to separate the treatment means that were significant. The results showed that there was no significant difference (p>0.05) in average feed intake among the broilers. There were significant differences (p<0.05) in average daily live weight gain, feed conversion ratio and final weight gain (market weight) among the broilers as influenced by different minerals-vitamins premix levels with improved performance recorded in 0.25% and 0.375% premix level. The least performance was obtained in 0.00% premix level. It was concluded that minerals-vitamins premix supplementation of broiler starter diet fed to Anak broilers from week 2 – week 5 was necessary for improved performance of the chickens. Optimum performance was obtained in 0.25% premix supplementation. 0.25% minerals-vitamins premix level could therefore be recommended for profitable production of broiler chickens in the prevailing tropical condition.