Abstract: AIM: The purpose of this study was to evaluate and compare the effectiveness of TENS and Ultrasound in reduction of pain in TMJ dysfunction and improvement in mouth opening. Materials and methods: Total 40 subjects with 54 joints were included in the study in which 20 subjects (28 joints) were treated by TENS for a duration of 30 min (8 patients had bilateral involvement) and 20 subjects (26 joints) by Ultrasound therapy (6 patients had bilateral involvement) which was given for duration of 10 min. Pain evaluation was done using VAS score at baseline and after the respective 6 consecutive sittings in both the groups. Mouth opening was evaluated using divider and scale at pre and post-operative sittings. Results: Pain reduction was more in TENS group than in Ultrasound with an improvement of 5.43 in TENS and 3.31 in Ultrasound on comparing baseline and 6th sitting and the difference was highly significant. A significant improvement in mouth opening was seen in TENS group with mean value of 2.15 mm. Conclusion: Both treatment modalities can be advised in TMD cases but the effect of TENS therapy has proved to be better than the effect of Ultrasound therapy in terms of reduction of pain intensity as well as in improving interincisal mouth opening.