Abstract: Background: Hijra community is a distinct community exists in Bangladesh and often degraded by the society. They are specifically recognised as third gender in South Asian countries like India, Bangladesh and considered as Tran’s female in all over the world. Most of the psychiatric prevalence done in Bangladesh earlier was considered about male and female gender ignoring the third genders. Objective: To find out the psychiatric morbidities among Hijra community. Method: This cross-sectional study was conducted over a period of one year in the treatment centres of the Non-Governmental Organization, from February 2019 to February 2020 Sample size: In order to get fixed sample of 50 clients we had to approach 63 clients among them 13 clients refused. Result: The mean age of the respondents was 32.94 ± 6.68 years and the range was 25 – 52 years. Almost two-thirds of the respondents were illiterate and only completed their primary education were 20.0%.Maximum of the respondent did not live either with their family or parents due to social stigma when hijras identified at the adolescent age that they were different from the male and female gender. 84.0% of the respondents lived with their Guru (Hijras are living in a group, in the group they have a leader elected by all hijras every body called the elected person’ Guru’) 14% with friend/partner. The respondents occupation was: begging 40%; singing and dancing30%; working as a sex worker 24% and others gets the change to work in the main stream of the population. As a sex partner, most of the respondents preferred males and the most preferable route was anus, and 18.0% of the respondents had a selective client.The average monthly income was more than 23000taka(U$ 271). According to DSM-5, Major Depressive Disorders was observed in 62% respondents, Substance/medication-induced psychotic disorder 20%; Histrionic Personality Disorder was observed in 14.0% respondents; and Anti-Social Personality Disorder 4%.