Musculoskeletal disorders (MSDs) negatively affect workers’ health, hence their productivity. It has immense cost implications on companies. Ergonomic intervention programs have been rolled out to reduce the occurrences of MSDs at workplaces. This review aims to examine the types and effectiveness of ergonomic intervention programs across multiple sectors. It sourced peer-reviewed articles from scholarly journal databases with keywords such as ergonomic intervention, ergonomic program and intervention program. Ergonomic intervention typically comprises three steps namely preliminary analyses, diagnosis and solution development. Interventions adopting multiple approaches to reduce identified risk factors and modifier interventions focusing on workers at risk are more effective than generic ones. Participatory approach increases the success of such interventions. Intervention practices could be classified as complete, shortened and turnkey where complete type follows the three intervention steps, shortened type compensates on or omits one step and turnkey type lacks diagnosis and solution development. While the intervention programs reviewed are generally effective, it remains largely unknown if the intervention and outcomes are sustainable and if compliance to ergonomic standards is met.