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Global Academic Journal of Medical Sciences
Volume-3 | Issue-06
Original Research Article
Comparison between Crystaloied and Colloid for Spinal Anesthesia for Elective Cesarean Delivery to Prevent Hypotension
Fakhruddin Ahmed, Mohammad Jakir Hossen Mollick, SK Ashraf Ulla, Rasheduzzaman, Nasreen Sultana, Salma Akter Walida
Published : Dec. 30, 2021
DOI : 10.36348/gajms.2021.v03i06.009
Abstract
Background: Hypotension is an important serious side effect of spinal anesthesia. Spinal anesthesia is a very popular technique for cesarean delivery in healthy pregnant women. However, hypotension secondary to the sympathetic vasomotor block associated with spinal anesthesia remains a common complication. Objective: To compare between crystaloied and colloid for spinal anesthesia for elective cesarean delivery to prevent hypotension. Materials and Methods: This prospective, randomized, controlled, double-blind study was performed at Upazilla Health Complex, Rupganj, Narayanganj, Bangladesh from January to June 2019. The study included 102 spinal anes¬thesia patients (ASA-I&II) who underwent elective cesarean surgery in 4 groups. In groups 1 and 2, 7 cc/kg of colloid solution was injected 20 min before and during spinal anesthesia, respec¬tively. In groups 3 and 4, 15 cc/kg of Hart Mann solution was injected 20 min before and during spinal anesthesia, respec¬tively. The BP, heart rate changes, vasopressor dose, nausea, vomiting, chest discomfort, and Apgar score were evaluated. Results: The BP decreased significantly when the patients changed position from supine to seating position (P = .001) and in the third minute after injecting the local anesthetic (P = .031) in all groups. Group 4 (24%) patients exhibited signif¬icant hypotension, whereas group 2 (16%) patients showed less hypotension. However, there was no statistically significant difference between the 4 groups (P = .31). There were no statis¬tical differences between the 4 groups in the Apgar of the fifth minute, vomiting, vertigo, and chest discomfort. Conclusions: Owing to high cost and probable side effects, colloid solutions are not recommended; and emergency cesareans need not be postponed to perform hydration before spinal anesthesia. The use of 1000 mL crystalloid co-load has similar effect to 500 mL colloid preload in reducing the incidence of hypotension after spinal anesthesia for elective cesarean delivery. Neither technique can totally prevent hypotension and should be combined with vasopressor use.

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