The term Cushing syndrome refers as the manifestations of excessive corticosteroids, most commonly due to supra physiologic doses of corticosteroids drugs and rarely due to spontaneous production of excessive corticosteroids by the adrenal cortex. In this case a 22 year old male patient came to the tertiary care hospital with the complaint of skin lesions over the body over three months. Patient taking injection of dexamethasone from the last 8 months, taking 2 doses within 15 days. On examination multiple erythematous, dry scaly plaques seen, multiple striae seen over bilateral crural folds, facial puffiness since eight months, abdominal distension. The patient was diagnosed with iatrogenic cushing's syndrome with tinea cruris with tinea corporis with acne eruption and also newly detected hypertension. Early detection of adverse effects can reduce the risk of occurrence of any other disease.