Background: Osteometric dimensions of the femoral bone have significant clinical and anthropological implications. However, there is a lack of comprehensive data on these dimensions specific to the Bangladeshi population. This study aims to fill this research gap by analyzing the osteometric dimensions of the lower end of the femoral bone among a sample set in Bangladesh. Methods: This cross-sectional observational study was conducted in three medical colleges in Dhaka, Bangladesh. A total of 50 dried femurs were collected based on specific inclusion and exclusion criteria. Osteometric measurements, including bicondylar width, medial and lateral condylar depths, intercondylar notch width, and intercondylar notch depth, were obtained using digital sliding calipers. Result: The study revealed notable differences in osteometric measurements between right and left femurs. For instance, 39.29% of right femurs had below-average Femoral Bicondylar Width (<65 mm) compared to 13.64% of left femurs. The mean Femur Medial Condylar Width was 31.05 mm with a standard deviation of 1.74 mm. Conclusion: The study provides valuable, region-specific osteometric data that has both clinical and anthropological implications. The findings are particularly important for the preparation of prosthetics and other supporting structures, which can be highly beneficial for both patients and medical practitioners.