The study investigated the influence of family variables on sexual molestation of secondary school students in Aba Education Zone, Abia State. Two research questions were answered using descriptive statistics. Two null hypotheses were tested with inferential statistics at .05 level of significance. The population of the study comprised all senior secondary school students in Aba Education Zone, Abia State. Simple random sampling technique was used in selecting 272 students for the study. A researcher made instrument tagged: family variables and sexual molestation questionnaire (FVSMQ) was used for data collection. The instrument was validated by an expert in measurement and evaluation while Cronbach alpha analysis was used for internal consistency of the instrument which yielded a coefficient of .80. The two hypothesis were tested using one-way Analysis of variance (ANOVA) and F-value obtained were significant at .05 level. It was therefore concluded that family structure and parents’ level of education influenced senior secondary school students’ experience on sexual molestation in Aba Education Zone, Abia State. Based on the findings, it was recommended among others that parents should ensure that lines of communication are kept open at home and closed family ties maintained so that children will never shy away from discussing sexual concerns with their parents.