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Global Academic Journal of Pharmacy and Drug Research
Volume-6 | Issue-04
Original Research Article
A Cross-Sectional Study on Clinical Profiles and Quality of Life of Patients with Neuropathic Pain
Shreya N. Jani, Arpit R. Patel, Mayank M. Prajapati, Kaushik Rana, Hemraj Singh Rajput, Rajesh Hadia
Published : Sept. 12, 2024
DOI : https://doi.org/10.36348/gajpdr.2024.v06i04.001
Abstract
Background: Due to nerve damage in the central and peripheral nervous systems, people with neuropathic pain experience acute pain. This study evaluated the health effects of neuropathic pain and different types of pain according to various neuropathies. Objective: To evaluate the clinical characteristics and QOL of neuropathic pain patients. Study the most frequently given medications, evaluate patients with various types of neuropathic pain, determine the characteristics of neuropathic pain, analyse the effects of neuropathic pain on general health. Materials and Methods: A total of 102 patients were enrolled according to the inclusion and exclusion criteria. Patients were interviewed using Short-Form McGill Pain Questionnaire-2, RAND 36 Item Health Survey 1.0 Questionnaire. Percentage, mean, chi square and standard deviation was used mainly in Statistical analysis. Result: Out of 102 patients, 44.12% were female, and 55.88% were male. Mean age of male and female was 46.60 and 47.42 years respectively. Radiculopathy patients were in the majority (43.1%), followed by peripheral neuropathy (37.3%), myelopathy (16.7%), sciatic neuropathy (2%), and brachial plexopathy (1%). Diabetes was highest to cause peripheral neuropathy. The most commonly prescribed drug was pregabalin, and combination were gabapentin and nortriptyline. The total means of all subscales of SF-MPQ-2 questionnaire was 4.56(2.10). Mean of physical component and emotional component summary was 34.30(17.54), and 42.38(15.74). Conclusion: Diabetes, trauma, weightlifting can also cause neuropathic pain. Diabetes was among top cause for peripheral neuropathy. Burning, itching, numbness, tingling, cold freezing pain were prevalent. The emotional function of patients was better than physical function.

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