Human-Centric Design Systems represent a defining transformation in industrial design, signalling a decisive movement away from product-oriented practices toward a deeper engagement with the lived realities, psychology, and ethics of human experience. This paper examines the conceptual, cognitive, and methodological foundations of human-centred design as the philosophical and practical nucleus of modern industrial design thinking. Drawing upon insights from phenomenology, cognitive psychology, ergonomics, and systems theory, it argues that design functions simultaneously as a rational discipline and a reflective practice—an iterative, empathy-driven process informed by participation and contextual understanding. Case studies such as Apple’s inclusive product philosophy, Dyson’s iterative engineering approach, and IDEO’s participatory redesign of healthcare environments illustrate how human-centred methods transcend traditional notions of utility and aesthetics, fostering emotional connection, cultural awareness, and sustainable innovation. The findings suggest that authentic design innovation emerges at the intersection of technological feasibility, social responsibility, and human well-being. The paper concludes that human-centric design must be recognised not merely as a methodology but as a developing epistemology—anchored in ethical responsibility, interdisciplinarity, and the enduring aim to enhance human life.